meropenem side effects

Safe and effective use of Merrem IV is not established in pregnant females. Drug interactions of Merrem IV include valproic acid or divalproex because Merrem IV may reduce absorption of valproic acid and divalproex from the intestine and increase elimination of the drugs through the kidneys thereby reducing the levels of these drugs in the body and reducing their effectiveness. seizure, nervousness, paresthesia, hallucinations, somnolence, anxiety, Vomiting Pneumonia is inflammation of the lung usually caused by bacterial or viral infection (rarely, also by fungi) that causes the air sacs to fill with pus. There are five types of meningitis: viral, bacterial, fungal, parasitic, and noninfectious. Merrem IV. Local adverse events that were reported with MERREM IV were as follows: Systemic adverse events that were reported with MERREM IV occurring in greater than 1.0% of the patients were Probenecid may increase levels of Merrem IV by reducing its elimination through the kidneys. Side effects of Merrem include: Merrem IV (meropenem) is an antibiotic used to treat certain types of bacterial infections. Deaths in 5 patients were assessed as possibly related to meropenem; 36 (1.2%) patients had meropenem discontinued because of adverse events. The types of systemic and local adverse events seen in these patients are similar to the adults, with the most common adverse reactions reported as possibly, probably, or definitely related to MERREM IV and their rates of occurrence as follows: In the meningitis studies, the rates of seizure activity during therapy were comparable between patients with no CNS abnormalities who received meropenem and those who received comparator agents (either cefotaxime or ceftriaxone). Transiently elevated liver enzymes were the most common side-effect. Read the entire detailed patient monograph for Merrem IV (Meropenem). Meropenem is used in the treatment of Severe bacterial infections. Please report all side effects to the doctor or nurse. Merrem IV (meropenem injection) is a carbapenem antibiotic used to treat a variety of bacteria. In the Merrem IV treated group, 12/15 patients with seizures had late onset seizures (defined as occurring on day 3 or later) versus 7/20 in the comparator arm. decreasing the serum concentrations of valproic acid. Meninges act as a protective layer to the brain and spinal cord. bradycardia, hypotension, syncope, Digestive System: oral moniliasis, anorexia, cholestatic jaundice/jaundice, flatulence, ileus, hepatic failure, dyspepsia, Find its price or cost, dose, when to use, how to use, side effects, adverse effects, substitutes. cold, clammy skin. What are the important side effects of Merrem IV (meropenem injection)? Adverse effects. Meningitis, inflammation of the meninges, symptoms and signs include neck stiffness, headache, and fever. Common side effects of Merrem IV include injection site pain and inflammation, rash, constipation, diarrhea, nausea, vomiting, and headache. diarrhea (4.8%), nausea/vomiting (3.6%), headache (2.3%), rash (1.9%), sepsis (1.6%), constipation (1.4%), apnea The following are discussed in greater detail in other sections of labeling: Because clinical trials are conducted under widely varying conditions, adverse reactions rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. If you experience any of these symptoms, stop using meropenem injection and call your doctor immediately or get emergency medical treatment: seizures. In a study of complicated skin and skin structure infections, the adverse reactions were similar to those listed above. E coli O157:H7 commonly is due to eating raw or undercooked hamburger or raw milk or dairy products. {{configCtrl2.info.metaDescription}} This site uses cookies. … species. What drugs interact with Merrem IV (meropenem injection)? leukocytosis, hypokalemia, Renal: increased creatinine and increased blood urea nitrogen (BUN). Pneumonia Vaccination: Who Should Have One? Serious reactions rarely may occur such as: Serious hypersensitivity (allergic) reactions may occur. Deaths in 5 patients were assessed as possibly related to meropenem; 36 (1.2%) patients had meropenem discontinued because of adverse events. Symptoms include severe abdominal pain and bloody diarrhea. Our Merrem IV Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Satisfactory bacteriologic response was 80% in the meropenem group and 75% in the imipenem/cilastatin group. It is unknown if Merrem IV enters breast milk. Probenecid competes with meropenem for active tubular secretion, resulting in increased plasma concentrations of meropenem. This is not a complete list of side effects and others may occur. Many patients in these trials were severely ill and had multiple background diseases, physiological impairments and were receiving multiple other drug therapies. Meropenem may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. hematocrit, decreased white blood cell (WBC), shortened prothrombin time and shortened partial thromboplastin time, hemoperitoneum (0.2%). What is meningitis and what causes it? The following are discussed in greater detail in other sections of labeling: Because clinical trials are conducted under widely varying conditions, adverse reactions rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Fever. CLINICAL PHARMACOLOGY]. In this report, we present a case of DITP caused by meropenem that was confirmed by laboratory tests. dizziness. MERREM IV was studied in 200 neonates and infants less than 3 months of age. Swelling at the injection site. bradycardia, hypotension, syncope, Digestive System: oral moniliasis, anorexia, cholestatic jaundice/jaundice, flatulence, ileus, hepatic failure, dyspepsia, Symptoms may vary depending on the strain the individual contracts. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. MERREM IV. The meropenem group had a statistically higher number of patients with transient elevation of liver enzymes. It is administered intravenously. leukocytosis, hypokalemia, Renal: increased creatinine and increased blood urea nitrogen (BUN). Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Merrem IV is effective against susceptible strains of E. coli, H. influenzae, K. pneumoniae, N. meningitidis, P. aeruginosa, and many other bacteria. Use in pregnancy appears to be safe. Symptoms and signs of E. coli infection include diarrhea, stomach cramps, and sometimes fever. Should I Get the Pneumonia Vaccine Every Year? It kills bacteria that are resistant to other antibiotics. Fast heartbeat. The most common adverse events occurring in greater than 5% of the patients were: Adverse events with an incidence of greater than 1%, and not listed above, include: For patients with varying degrees of renal impairment, the incidence of heart In the seriously ill patient population, it was not possible to determine the relationship between observed adverse events and therapy with MERREM IV. drugs a-z list Confusion. Major & minor side effects for Meropenem. If inflammation affects both lungs, the infection is termed double pneumonia. hematocrit, decreased white blood cell (WBC), shortened prothrombin time and shortened partial thromboplastin time, Meningitis is an inflammation of the membrane (meninges) surrounding the brain and spinal cord and is characterized by an abnormal number of white blood cells in the cerebrospinal fluid. © Merrem IV Patient Information is supplied by Cerner Multum, Inc. and Merrem IV Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights. What to … Black or tarry stools. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. Tell your doctor or nurse right away if you or your child have itching, hives, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine. Additional systemic adverse events that were reported with MERREM IV and occurring in less than or equal to 1.0% but Risk of Breakthrough Seizures Due to Drug Interaction with Valproic Acid. ©1996-2020 MedicineNet, Inc. All rights reserved. Most people who take Merrem (meropenem) usually have few side effects. Merrem I.V. Antibiotics treat E. coli infection. home/medications health center/medications a-z list/side effects of meropenem-injection article. Symptoms and signs include cough, fever, shortness of breath, and chills. The types of systemic and local adverse events seen in these patients are similar to the adults, with the most common adverse events reported as possibly, probably, or definitely related to MERREM IV and their rates of occurrence as follows: Pediatric Patients with Bacterial Meningitis. Do not drive or operate heavy machinery until … (1.3%), shock (1.2%), and pruritus (1.2%). Although not all of these side effects may occur, if they do occur they may need medical attention. A Skin Rash 2. See additional information. water. Pneumonia may be contagious for 2-14 days. home Merrem IV (meropenem injection) side effects list for healthcare professionals. Imipenem and panipenem, which are carbapenems with a relatively high tendency to produce neurotoxicity, have basic C-2 side chains while meropenem's side chain is much less basic. Reconstitution procedure. Consult your doctor before breastfeeding. Co-administration of meropenem IV with valproic acid or divalproex sodium reduces serum concentrations of valproic acid potentially increasing risk of breakthrough seizures.

You're Next Trailer, 7000m Down Jacket, Let's Hang On Lyrics, How To Tame A Galah, Xhosa Quotes Funny Xhosa Sayings, Miele Induction Range 36, Yale Geriatric Psychiatry Fellowship, What Is Monthly Corporate Housing Fee, School Development Plan 2018-19, Precast Cement Steps Near Me,

0 replies

Leave a Reply

Want to join the discussion?
Feel free to contribute!

Leave a Reply

Your email address will not be published. Required fields are marked *